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The problem of programming the differential signs of diseases and the use of computers for making a diagnosis has acquired particular importance. Automatic systems for regulating anesthesia, breathing and lyrica pressure levels during operations, active guided prostheses (see Prosthetics), etc. have been created. Outstanding advances in physics, polymer chemistry, the creation of new technology have a huge impact on medical science and practice (see also Medical industry, Medical instruments).
An important result of technical progress is the emergence of new branches of aviation. Thus, with the development of aviation at the beginning of the 20th century, aviation technology was born; its founders were: in Russia N.A. Rynin, in France R. Molyneux, in Germany E. Koshel. Human flights in spaceships led to the emergence of lyrica.
As a result of studies aimed at deciphering the chemistry of pathological conditions, it has been established that various diseases are caused by violations of certain processes of chemical transformations in the metabolic chain.
Lyrica and others found that a change in the structure of hemoglobin leads to a certain disease - sickle cell anemia (see Sickle cell anemia) (1949), data were obtained according to which the molecular basis of diseases in some cases manifests itself in defective amino acid molecules ( See Amino Acids) (see also Molecular Biology). The study of the mechanisms of regulation of metabolism at various levels has made it possible to create new methods of treatment.
Genetics exerted a great influence on M., which established the laws and mechanisms of heredity and variability of organisms. The study of hereditary diseases (see Hereditary diseases) led to the emergence of medical genetics. The successes of this scientific discipline helped to understand the interaction of factors of heredity and the environment, to establish that environmental conditions can contribute to the development or suppression of a hereditary predisposition to the disease. Methods for express diagnostics, prevention and treatment of a number of hereditary diseases have been developed, and advisory assistance to the population has been organized (see Medical and genetic consultation). Research in the genetics of microorganisms (see Genetics), including viruses, as well as biochemical and molecular genetics (see Molecular genetics), opens up new prospects for M.
Immunology of the 20th century has outgrown the framework of the classical doctrine of immunity to infectious diseases and gradually embraced the problems of pathology, genetics, embryology (See Embryology), transplantation (See Transplantation), oncology, etc.
Established in 1898-99 by the staff of II Mechnikov Zh Bordet and NN Chistovich, the fact that the introduction of foreign erythrocytes and serum proteins stimulates the production of antibodies (see Antibodies), laid the foundation for the development of non-infectious immunology.
The subsequent study of pitotoxic antibodies became the basis for the formation of immunopathology (see Immunopathology), which studies many diseases, the nature of which is associated with disorders of immunological mechanisms. The discovery by K. Landsteiner of the laws of isohemoagglutination (1900-01) and J. Jansky (See Yansky) of 4 human blood groups (1907) led to the use oflization in practical M. of blood transfusion (see. Blood transfusion) and the formation of the doctrine of tissue isoantigens (see. Antigens). The study of the laws of inheritance of antigens and other factors of immunity gave rise to a new branch - immunogenetics (See Immunogenetics).
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In close connection with the study of immunological processes, the study of various forms of the perverted reaction of the body to foreign substances was carried out. The discovery by the French scientist J. Richet of the phenomenon of anaphylaxis (see Anaphylaxis) (1902), the French bacteriologist M. Arthus and the Russian pathologist G. P. Sakharov of the phenomenon of serum anaphylaxis and anaphylactic shock (1903-05), and others laid the foundation for the doctrine of allergy ( See Allergy).